CiteScore: 5.0     h-index: 22

A Search for Novel Antidiabetic Agents Using Ligand-Based Drug Design and Molecular Docking Studies Employing Human Intestinal Maltase-Glucoamylase as Model Enzyme
A Search for Novel Antidiabetic Agents Using Ligand-Based Drug Design and Molecular Docking Studies Employing Human Intestinal Maltase-Glucoamylase as Model Enzyme

Khalifa Sunusi Aminu; Adamu Uzairu; Stephen Eyije Abechi; Gideon Shallangwa Adamu; Abdullahi Bello Umar

Volume 6, Issue 2 , April 2023, , Pages 155-171

https://doi.org/10.22034/ajca.2023.387041.1355

Abstract
  This study employed quantitative structure-activity relationship (QSAR) to predict the inhibitory activities of N-(alkyl/aryl)-2-chloro-4-nitro-5-[(4-nitrophenyl) sulfamoyl] benzamide ...  Read More
Exploration of Anticancer Potential of Novel Pyrrolo[2,3-b]pyridine Derivatives Targeting V600E-BRAF Kinase: Molecular Docking, Pharmacokinetic and DFT Studies
Exploration of Anticancer Potential of Novel Pyrrolo[2,3-b]pyridine Derivatives Targeting V600E-BRAF Kinase: Molecular Docking, Pharmacokinetic and DFT Studies

Abdullahi Bello Umar; Adamu Uzairu

Volume 5, Issue 4 , October 2022, , Pages 271-286

https://doi.org/10.22034/ajca.2022.356191.1322

Abstract
  V600E-BRAF mutation has been detected in several malignant tumours. Developing potent V600E-BRAF inhibitors is considered an essential step in curing diverse cancer types. In this work, ...  Read More
Pharmacokinetics Studies of some Diaryl Pyrimidinamine Derivatives as Anti-Cancer Agent: In-Silico Drug Design and Molecular Docking
Pharmacokinetics Studies of some Diaryl Pyrimidinamine Derivatives as Anti-Cancer Agent: In-Silico Drug Design and Molecular Docking

Sagiru Hamza Abdullahi; Adamu Uzairu; Gideon Adamu Shallangwa; Sani Uba; Abdullahi Bello Umar

Volume 5, Issue 4 , October 2022, , Pages 320-332

https://doi.org/10.22034/ajca.2022.357747.1325

Abstract
  The cost and duration of novel drug discovery and synthesis have been the significant drawbacks to the chemotherapeutic treatment of breast cancer. To combat these challenges, a validated ...  Read More