@article { author = {Norouzi, Nima}, title = {Thermodynamic and Exergy Analysis of Cogeneration Cycles of Electricity and Heat Integrated with a Solid Oxide Fuel Cell Unit}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {244-257}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.283638.1255}, abstract = {Among the items that have been widely used as a solution to reduce energy consumption and air pollution are cycles of simultaneous generation of electricity and heat or CHP. In such cycles, the gas turbine’s exhaust gases enter the steam production unit to produce the required steam or hot water. In the meantime, and due to the increasing use of oxidized fuel cells, combined circuits including fuel cells, gas turbines, and recovery boilers have been considered. In this paper, the combined cycle, including fuel, gas turbine, and recovery boiler, was thermodynamically analyzed, and its performance results are compared with a normal CHP cycle. Electrochemical and chemical modeling of fuel cells and exergy and thermodynamic analysis of all cycle components have been performed. In the cycle, performance changes with basic cycle parameters such as the temperature of the combustion products entering the gas turbine, the boiler steam pressure, the pinch point, the flow intensity, and the fuel cell stack temperature were analyzed. According to the results, the efficiency of the combined cycle with a fuel cell, is much higher, 61% compared with the 50% of the normal CHP.}, keywords = {SOFC,cogeneration,CHP,Exergy analysis}, url = {http://www.ajchem-a.com/article_131440.html}, eprint = {http://www.ajchem-a.com/article_131440_79dfd90ae60456d7b7d93e01d1fe0033.pdf} } @article { author = {Esan, Olaseni and Bankole, Owolabi and Olanrewaju, Owoyomi and Moses, Adeyemo}, title = {Conductometric Approach to the Thermodynamic of Micellization of Anionic Surfactants in the Presence of Procaine Hydrochloride}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {258-269}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.285094.1258}, abstract = {This study underscores the teleology of micellization behaviours of sodium dodecyl sulphate (SDS) and sodium lauroyl sarcosinate (SLS), an anionic surfactant. The configuration of SDS/SLS water soluble in the presence of 4.0 x 10-5 moldm-3 aqueous solution of procaine hydrochloride within the temperature range of 293.15 K to 313.15 K was observed. Critical micelle concentration (CMC), and degree of counter ion binding (β) were determined from conductivity data. The CMC of SDS and SLS decreased to reach a minimum (T= 308.15 K and 303.15 K for SDS and SLS) and then increased with increasing temperature. On applying mass action model, the obtained CMC values were used to determine the thermodynamic parameters (i.e. free energy of micellization (ΔG°m), enthalpy of micellization (ΔH°m) and entropy of micellization (ΔS°m)). As a function of temperature, the  value was negative and the negativity was enhanced in surfactants-PHC medium as compared with aqueous medium.  This is an indication that spontaneity increases in micelle formation in the SDS+PHC and SLS+PHC systems than water. Entropy-enthalpy compensation were observed on applying Lumry-Rajender-entropy compensation model. The observed compensation temperatures, Tc, for SDS and SLS, were not the same with and without PHC. SDS had Tc values of 302.8±3.14 and 307.7±1.63, while for SLS, Tc=305.46±3.14 and 307.33±2.18.  A clear indication of enthalpy–entropy compensation phenomenon was observed.}, keywords = {sodium dodecyl sulphate,sodium lauroyl sarcosinate,self-aggregation,enthalpy– entropy compensation,Micellization}, url = {http://www.ajchem-a.com/article_132956.html}, eprint = {http://www.ajchem-a.com/article_132956_c0cb559ccb42b15e0c3cbdb4cbaf9e51.pdf} } @article { author = {Bashandeh, Zahra and Dehno Khalaji, Aliakbar}, title = {Effective Removal of Methyl Green from Aqueous Solution Using Epichlorohydrine Cross-Linked Chitosan}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {270-277}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.285520.1259}, abstract = {Epichlorohydrin cross-linked chitosan (EP-Cs) was prepared was characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), thermal gravimetry (TG-DTA) and differential calorimetric analysis (DSC), and used as adsorbent for methyl green (MG) removal. Epy-Chit was soaked in methyl green solution with concentration of 40 mg/L using a batch adsorption system, to measure the adsorption capacity of the EP-Cs and the percentage of MG removed from the aqueous solution. The optimum MG adsorption on EP-Cs occurred at pH 7.8, agitation time of 60 minute and adsorbent dosage of 0.02 g were observed. Adsorption results show that the EP-Cs exhibited the excellent performance for the MG removal from aqueous solution. This study suggests that EP-Cs could be explored as an adsorbent for removing other organic pollutants.}, keywords = {Epichlorohydrin,Cross-linked,Chitosan,Adsorbent,Methyl green}, url = {http://www.ajchem-a.com/article_133377.html}, eprint = {http://www.ajchem-a.com/article_133377_217bd07b899168f799c77d16195b072d.pdf} } @article { author = {Prasad, Ashwini and Nellikaya, Gopalakrishna and Nazareth, Ronald}, title = {Action of 4-[(Z)-(4-Methoxybenzylidene)amino]-5-methyl-4H-1,2,4-triazole-3-thiol as Chemosensor for the Trace Amount of Copper in Aqueous Media}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {278-287}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.276483.1252}, abstract = {This research study evaluates a novel, sensitive, and selective spectrophotometric method for the estimation of copper(II) by using a new chromogenic reagent 4-[(Z)-(4-methoxybenzylidene) amino]-5-methyl-4H-1,2,4-triazole-3-thiol (MAMTT) (Schiff base). The maximum absorbance was found to be at 613 nm. Experimental conditions were optimized. Beer’s law was seen in 12.7-50.83 µg/mL of copper concentration range. Calculated molar absorptivity, detection limit and quantification limit of the complex were 0.307x104 L mol-1.cm-1, 6.328 µg/cm3 and 19.177 µg/cm3, respectively. The study of interference of common ions was carried out. The current process was enforced for the estimation of copper in water samples.}, keywords = {Spectrophotometry,MAMTT,Copper(II) determination}, url = {http://www.ajchem-a.com/article_133695.html}, eprint = {http://www.ajchem-a.com/article_133695_199481810692c0bcdea2950b7ec29bb7.pdf} } @article { author = {Oyeneyin, Oluwatoba and Abayomi, Toluwalope and Ipinloju, Nureni and Agbaffa, Eric and Akerele, Daniel and Arobadade, Oluwatobiloba}, title = {Investigation of Amino Chalcone Derivatives as Anti-Proliferative Agents against MCF-7 Breast Cancer Cell Lines-DFT, Molecular Docking and Pharmacokinetics Studies}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {288-299}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.285869.1261}, abstract = {Breast cancer is one of the most lethal diseases that has resulted in many deaths in the world. Development of new compounds and repurposing of approved drugs have become very attractive in the field of drug design. Computer-aided drug design has become popular because it is cost effective and time saving. In this work, the molecular descriptors of some amino chalcone derivatives were derived using the density functional theory; some of the optimized molecules were also docked at the active site of a human serine/threonine-protein kinase receptor, 3FC2, to obtain their binding affinities. The potential surface energies for all compounds range from -190.4 kJ/mol to -172.3 kJ/mol for low energy regions and 199.8 kJ/mol to 263.3 kJ/mol for high energy regions indicating that the ligands would bind well with receptors. All compounds have higher binding energy than the standard drug, 5-Fu (-6.19 kcal/mol) when docked into the active site of 3FC2 and their mode of interaction are just like it was in 5-Fu. Our observations are still subject to confirmation via clinical and pre-clinical investigations.}, keywords = {Amino Chalcones,computer-aided drug design,Molecular Modeling,Molecular docking,breast cancer,Pharmocokinetics}, url = {http://www.ajchem-a.com/article_133740.html}, eprint = {http://www.ajchem-a.com/article_133740_dc901fdc8e370a31a915ff73bf2962ec.pdf} } @article { author = {Mighani, Hossein and Sajadinia, Seied Morteza and Nasr-Isfahani, Hossein and Bakherad, Mohammad}, title = {Synthesis of New Polyurethanes Based on 2,3-Dihidro-1,4-Phthalazinedione}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {300-307}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.286663.1262}, abstract = {In this work, to synthesis the 2-(2-hydroxy ethyle)-2,3-dihydro-1,4-phthalazinedione and 2,3-bis(2-hydroxyethyle)-2,3-dihydro-1,4-phthalazinedione, 2-boromoethanol was reacted with phthalhydrazide in DMAc at presence of triethylamine in mole ratio of 1.5:1 and 3:1 respectively. The structure of the monomers was evaluated using the IR and 1H-NMR spectra. New polyurethanes were synthesized by reaction of the monomers with various diisocyanates including, tolylene diisocyanate, isophorane diisocyanate and hexamethylene diisocyanate. The measured viscosity for these polymers was found to be at the range of 0.45-0.6 dlg-1. The structure of the polymers was proved by IR, 1HNMR spectra and CHN analysis. The TGA and DTG results confirmed high thermal stability for the synthesized polymers.}, keywords = {Polyurethanes,IR-Viscometery,Thermal analysis,Differential thermal gravimetric analysis}, url = {http://www.ajchem-a.com/article_134379.html}, eprint = {http://www.ajchem-a.com/article_134379_b793f9305daae334a8ce43e1bc899d2d.pdf} } @article { author = {Lawan, Mohammed and Mai Garba, Idris}, title = {Medicinal Value of Some Bioactive Compounds from Three Species of Striga Grass (S. hermontheca, S. aciatica and S. gesnerioides) Extractions}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {308-316}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.282292.1263}, abstract = {The control of Striga infestation in agricultural produce proved to be difficult especially in Africa. This study therefore aimed at finding a way of making the plant useful. The results revealed that all the plants contain flavonoids, glycosides, tannins, phenols, oxalate and carbohydrates. Alkaloid and saponnins were only found to be present in S. gesnerioides. A relative high amount of flavonoids (6.86+0.42 mgRutin/g) and phenols in the stem (9.36+0.55 mgGAE/g) of S. gesnerioides closely followed by leaves of S. hermontheca 4.06+0.25 mgRutin/g, 13.06+0.32 mgGAE/g respectively. The presence of these bioactive components indicates the plant’s potential as a source of major secondary metabolites that may serve as novel medicines. The percentage inhibition concentration at 50% (IC50) of S. hermontheca stem, root and leaves were 73.13 µg/g, 41.39 µg/g and 207.01 µg/g respectively. The stem, roots and haustorium of S. gesneriodes indicated an IC50 of 70.39 µg/g, 55.33 µg/g and 55.07 µg/g respectively while S. aciatica 52.35 µg/g, and 72.71 µg/g respectively. Compared to standard ascorbic acid with IC50 of 57.78 µg/g, the three species have relative significant antioxidant activity. Further successive extraction, purification and characterization of the bioactive components found present in this research will make further research interesting.}, keywords = {Striga,Antioxidant,nutrients,Accumulation,Medicinal value,Bioactive components}, url = {http://www.ajchem-a.com/article_134610.html}, eprint = {http://www.ajchem-a.com/article_134610_a7537669bead004ec3cf00b4ebb16dc3.pdf} } @article { author = {Dehno Khalaji, Aliakbar and Machek, Pavel and Jarosova, Marketa}, title = {α-Fe2O3 Nanoparticles: Synthesis, Characterization, Magnetic Properties and Photocatalytic Degradation of Methyl Orange}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {317-326}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.292396.1268}, abstract = {α-Fe2O3 magnetic nanoparticles (MNPs) (Fe-1, Fe-2 and Fe-3) were prepared by a simple wet chemical precipitation route and characterized by Fourier transform infrared spectroscopy (FT‑IR), X‑ray diffraction (XRD) and transmission electron microscopy (TEM). The magnetic behaviors of the as‑prepared Fe3O4 nanoparticles were done using vibrating sample magnetometer (VSM). In addition, the as‑prepared α‑Fe2O3 nanoparticles were used as photocatalyst for degradation and removal of methyl orange (MO) dye under visible light irradiation from aqueous solution. The influence of various parameters such as contact time and dosage of catalyst have been examined and discussed. The studies revealed that the degradation of MO reached to 95% (Fe‑1), 88% (Fe‑2) and 62% (Fe‑3) within 120 min by increasing of catalyst dosage from 0.02 g to 0.06 g.  Degradation rates of MO by Fe‑1, Fe‑2 and Fe‑3 were 0.0249, 0.0177 and 0.0081 min‑1, respectively, indicating that the degradation depends on the crystalline size and morphology of the α‑Fe2O3 magnetic nanoparticles.}, keywords = {α-Fe2O3,Magnetic nanoparticles,photocatalyst,degradation}, url = {http://www.ajchem-a.com/article_134768.html}, eprint = {http://www.ajchem-a.com/article_134768_71a22417e136425b019f013ec066d0db.pdf} } @article { author = {Mezoughi †, Aysha and Abdussalam-Mohammed, Wanisa and Abdusalam †, Ashraf}, title = {Synthesis and Molecular Docking Studies of Some Thiohydantoin Derivatives as Potential Anticancer and Antimicrobial Agents}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {327-338}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.291823.1266}, abstract = {2-Thiohydantoin derivatives are most remarkably known because of their extensive applications including, hypolipidemic, anticarcinogenic, antimutagenic, antifungal, and antibacterial. For this reason, three of 5-aryl-2-thiohydantion derivatives (3-5) and the conversion of 2-thiohydantoin to thiol ether (7) by alkylation with methyl bromoacetate are successfully synthesized. To evaluate and understand the interactions and the orientation between the synthesized compounds and binding pocket of cancer and bacterial protein receptor, molecular docking studies using the Auto dock Vina were performed against three proteins including; isocitrate dehydrogenase (IDH1, PDB: 4UMX) and two bacterial proteins (LasR-OC12 HSL complex PDB:3IX3, and β-ketoacyl-acyl carrier protein synthase, PDB:1FJ4). The docking results demonstrated that lower free energy of binding (FEB) was obtained from the synthesized compounds ranging from −5.1 to −9.6 kcal/mol for 3IX3, −4.9 to −7.8 kcal/mol for 1FJ4, and −4.4 to −8.5 kcal/mol for 4UMX. }, keywords = {Thiohydantoin derivatives,Anticancer,Antimicrobial agents,Proteins,Amino acids,IDH1,Molecular docking}, url = {http://www.ajchem-a.com/article_134894.html}, eprint = {http://www.ajchem-a.com/article_134894_f0312def6729c29ab930db6722a79c85.pdf} } @article { author = {Oluwafemi, Kola}, title = {ESKAPE Pathogens: Structure-Activity Relationships of 2,4-Diarylquinolines}, journal = {Advanced Journal of Chemistry, Section A}, volume = {4}, number = {4}, pages = {339-344}, year = {2021}, publisher = {Sami Publishing Company}, issn = {2645-7768}, eissn = {2645-5676}, doi = {10.22034/ajca.2021.297580.1278}, abstract = {Drug resistance by persisters is a global issue that requires urgent attention. Quinolines and quinolones have proven to be important cores in several bioactive organic chemotypes, based on this, the antimicrobial activity of six derivatives of 2,4-diarylquinolines was evaluated using the disc diffusion method at 5-20 µM/mL. The bioactivity evaluation was conducted on four bacteria examples, two of which are ESKAPE bacteria (Staphylococcus aureus, Streptococcus pneumonia, Escherichia coli and Pseudomonas aeruginosa). The results indicated promising minimum inhibitory concentrations (5 and 10 µM/mL in some cases) and encouraging zones of inhibition against the 4 germs while interesting and reasonable structure-activity relationships were established at the end of the study.}, keywords = {2,4-Diarylquinolines,ESKAPE Pathogen,Antimicrobial Resistance,Minimum inhibitory concentration,Zone of inhibition}, url = {http://www.ajchem-a.com/article_135355.html}, eprint = {http://www.ajchem-a.com/article_135355_8e225ab609979a7397232633e02e25eb.pdf} }