CiteScore: 5.0     h-index: 22

(S)-N-(4-Carbamoylphenyl)-8-Cyclopropyl-7-(Naphthalen-1-ylmethyl)-5-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-a]Pyridine-3-Carboxamide, A Better Inhibitor of SARS-Cov-2 Spike Glycoprotein Than Some Standard Drugs: A Computational Prediction
(S)-N-(4-Carbamoylphenyl)-8-Cyclopropyl-7-(Naphthalen-1-ylmethyl)-5-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-a]Pyridine-3-Carboxamide, A Better Inhibitor of SARS-Cov-2 Spike Glycoprotein Than Some Standard Drugs: A Computational Prediction

Emmanuel Israel Edache; Adamu Uzairu; Paul Andrew Mamza; Gideon Adamu Shallangwa

Volume 6, Issue 1 , January 2023, , Pages 17-30

https://doi.org/10.22034/ajca.2023.362410.1333

Abstract
  The appearance of severe acute respiratory syndrome coronavirus 2 (COVID-19) is at its peak; with the growing number of people infected with COVID-19, there is an urgent need to find ...  Read More
In-silico Design of Oxadiazole Hybrids as Potential Inhibitors of Dengue Virus NS2B-NS3 Protease
In-silico Design of Oxadiazole Hybrids as Potential Inhibitors of Dengue Virus NS2B-NS3 Protease

Samuel Ndaghiya Adawara; Gideon Shallangwa Adamu; Paul Andrew Mamza; Ibrahim Abdulkadir

Volume 5, Issue 2 , April 2022, , Pages 118-137

https://doi.org/10.22034/ajca.2022.320210.1291

Abstract
  This study aimed at designing highly potent dengue virus (DENV) inhibitors targeting the NS2B-NS3 protease from 1,2-benzisothiazol-3(2H)-one-1,3,4-oxadiazole (BTZO) hybrid through quantitative-structure-activity ...  Read More
Chemoinformatic Design of Phthalazinone Analogues as Novel Dengue Virus NS2B-NS3 Protease Inhibitors with Enhanced Pharmacokinetics
Chemoinformatic Design of Phthalazinone Analogues as Novel Dengue Virus NS2B-NS3 Protease Inhibitors with Enhanced Pharmacokinetics

Samuel Ndaghiya Adawara; Gideon Shallangwa Adamu; Paul Andrew Mamza; Ibrahim Abdulkadir

Volume 5, Issue 2 , April 2022, , Pages 175-189

https://doi.org/10.22034/ajca.2022.322426.1297

Abstract
  Dengue fever is the most common and important arthropod-borne viral illness in humans. However, no effective medications or vaccinations exist to prevent this condition. The dengue ...  Read More