%0 Journal Article %T Surfactant-Assisted Co-Precipitation Synthesis of Ca-Doped Ceria Nanoparticles for Antibacterial Applications %J Advanced Journal of Chemistry, Section A %I Sami Publishing Company %Z 2645-7768 %A Amar, Ibrahim Ali %A Shamsi, Shamsi A. %A Saheem, Ruqayah M %A Altawati, Amdallah A %A Abdulkarim, Mohammed A %A Abdulqadir, Mabroukah A %A Abdalsamed, Ihssin A %D 2021 %\ 01/01/2021 %V 4 %N 1 %P 10-21 %! Surfactant-Assisted Co-Precipitation Synthesis of Ca-Doped Ceria Nanoparticles for Antibacterial Applications %K Cerium oxide nanoparticles %K Surfactant %K Co-precipitation method %K Antibacterial Activity %K Drug-resistance bacteria %K Optical density measurement %R 10.22034/ajca.2020.247227.1210 %X Antibiotic-resistant pathogenic bacteria (e.g., multi-drug resistant bacteria, MDR) have been one of the major threats to human health. Nanoparticles, the newly emerging tools, hold the promise to solve the antibiotic resistance-related problems. This study aimed at evaluating the antibacterial activities of Ca-doped ceria nanoparticles (CDC) against the Gram-negative bacteria (Pseudomonas aeruginosa and Klebsiella pneumoniae) and Gram-positive bacteria (Staphylococcus aureus) using optical density measurement. Co-precipitation method was used to synthesize the Ca-doped ceria nanoparticles with and without addition of cetyltrimethylammonium bromide (CTAB, cationic surfactant). The prepared nanoparticles were characterized using the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and UV-Vis spectroscopy. The XRD results demonstrated that, the CDC-CTAB nanoparticles (synthesized via CTAB-assisted co-precipitation method) had the smaller crystallite size (16.26 nm) and higher specific surface area (56.72 m2/g) compared to the CTAB-free synthesized sample (CDC nanoparticles). In addition, the CDC-CTAB nanoparticles exhibited a better inhibition percentage of bacteria growth (29.54-34.08%) against both the Gram-negative and Gram-positive bacteria. In terms of materials cost and toxicity, Ca-doped ceria nanoparticles can be considered as promising materials and, their biological activity might be evaluated against other microorganisms. %U http://www.ajchem-a.com/article_117941_4bf91ee78d1298925e045a59de3a7acf.pdf