TY - JOUR ID - 117941 TI - Surfactant-Assisted Co-Precipitation Synthesis of Ca-Doped Ceria Nanoparticles for Antibacterial Applications JO - Advanced Journal of Chemistry, Section A JA - AJCA LA - en SN - 2645-7768 AU - Amar, Ibrahim Ali AU - Shamsi, Shamsi A. AU - Saheem, Ruqayah M AU - Altawati, Amdallah A AU - Abdulkarim, Mohammed A AU - Abdulqadir, Mabroukah A AU - Abdalsamed, Ihssin A AD - Department of Chemistry, Faculty of Science, Sebha University, Sebha, Libya AD - Department of Botany (Microbiology Lab), Faculty of Science, Sebha University, Sebha, Libya AD - Department of Chemistry, Faculty of Science, Sebha University, Sebha, Libya Y1 - 2021 PY - 2021 VL - 4 IS - 1 SP - 10 EP - 21 KW - Cerium oxide nanoparticles KW - Surfactant KW - Co-precipitation method KW - Antibacterial Activity KW - Drug-resistance bacteria KW - Optical density measurement DO - 10.22034/ajca.2020.247227.1210 N2 - Antibiotic-resistant pathogenic bacteria (e.g., multi-drug resistant bacteria, MDR) have been one of the major threats to human health. Nanoparticles, the newly emerging tools, hold the promise to solve the antibiotic resistance-related problems. This study aimed at evaluating the antibacterial activities of Ca-doped ceria nanoparticles (CDC) against the Gram-negative bacteria (Pseudomonas aeruginosa and Klebsiella pneumoniae) and Gram-positive bacteria (Staphylococcus aureus) using optical density measurement. Co-precipitation method was used to synthesize the Ca-doped ceria nanoparticles with and without addition of cetyltrimethylammonium bromide (CTAB, cationic surfactant). The prepared nanoparticles were characterized using the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and UV-Vis spectroscopy. The XRD results demonstrated that, the CDC-CTAB nanoparticles (synthesized via CTAB-assisted co-precipitation method) had the smaller crystallite size (16.26 nm) and higher specific surface area (56.72 m2/g) compared to the CTAB-free synthesized sample (CDC nanoparticles). In addition, the CDC-CTAB nanoparticles exhibited a better inhibition percentage of bacteria growth (29.54-34.08%) against both the Gram-negative and Gram-positive bacteria. In terms of materials cost and toxicity, Ca-doped ceria nanoparticles can be considered as promising materials and, their biological activity might be evaluated against other microorganisms. UR - http://www.ajchem-a.com/article_117941.html L1 - http://www.ajchem-a.com/article_117941_4bf91ee78d1298925e045a59de3a7acf.pdf ER -