TY - JOUR ID - 146780 TI - Complexation of Ag(I) with 8-Hydroxyquinoline: Synthesis, Spectral Studies and Antibacterial Activities JO - Advanced Journal of Chemistry, Section A JA - AJCA LA - en SN - 2645-7768 AU - Elsherif, Khaled Muftah AU - Aberrwaila, Hasan AU - Aburowais, Abdulaziz Suliman AU - Etwaish, Ali Mansour AU - Elassawi, Ali Meftah AD - Chemistry Department, Faculty of Science, University of Benghazi, Benghazi, Libya AD - Chemistry Department, Faculty of Science, Misurata University, Misurata, Libya AD - Department of Food Industries, Faculty of Agriculture, Misurata University, Misurata, Libya AD - Medical Laboratory Department, Faculty of Medical Technology, Misurata University, Misurata, Libya Y1 - 2022 PY - 2022 VL - 5 IS - 2 SP - 138 EP - 146 KW - Silver(I) KW - 8-Hydroxyquinoline KW - UV-Visible Spectrometry KW - Antibacterial Activity DO - 10.22034/ajca.2022.322123.1294 N2 - In the present study, silver complex with 8-hydroxyquinoline (8-HQ) was synthesized and characterized by FT IR and UV-VIS spectroscopic methods. The stoichiometric ratio, molar absorptivity, and formation constant were evaluated using UV-VIS spectrophotometric method. Both oxygen and nitrogen atoms from 8-HQ were included in the complex formation as stated by the spectral data. The UV-VIS spectrophotometric data indicated the formation of (1:1) complex with a formation constant of 4.2x108. Also, the antimicrobial effects of the ligand and the complex were examined in vitro. The diffusion style was used to investigate the antimicrobial activity on some chosen gram-positive and gram-negative bacteria. The ligand and its metal complex possessed antibacterial activity for particular bacteria such as Staphylococcus aureus and Proteus spp. The antimicrobial activity of the complex was higher with gram-negative bacteria. Meanwhile, the 8-HQ was found to have an appreciably higher capability to inhibit the growth of the gram-positive bacteria. UR - http://www.ajchem-a.com/article_146780.html L1 - http://www.ajchem-a.com/article_146780_fa8270d9ed7ef57677e933058477fd55.pdf ER -