CiteScore: 4.9     h-index: 21

Document Type : Original Research Article


Department of chemistry, Faculty of Science, University of agriculture, Makurdi, Benue state, Nigeria



Phytochemical screening of Terminalia schimperiana (Combretaceae) Root Bark showed presence of flavonoids, tannins, steroid carbohydrates and terpenoides in n-hexane, ethylacetate and methanol as solvents of extraction. Isolated stigmasterol from Terminalia schimperiana was a white-yellow crystal which characterized using 1H-NMR, 13C-NMR, COSY, HSQC and HMBC spectral techniques. Research studies clearly revealed that Terminalia schimperiana root bark extract has potential to be exploited in the pharmaceutical firm in the search for stigmasterol related drug from nature.

Graphical Abstract

Phytochemical Analyses of Terminalia Schimperiana (combretaceae) Root Bark Extract to Isolate Stigmasterol


Main Subjects

[1]. I.S. Akande, O.A. Adewoyin, U.F. Njoku, S.S. Awosika, J.Drug. Metabolism Toxicol., 2012, 3, 118.
[2]. Igoli, J. O., Gray, A. I., Clements, C. J., & Mouad, H. A. Anti-Trypanosomal Activity and cytotoxicity of some compounds and extracts from Nigerian Medicinal Plants. In Phytochemicals-Bioactivities and impact on Health. IntechOpen. 2011
[3]. I. Toma, Y. Karumi, M.A. Geidam, Afr. J. Pure Appl. Chem., 2009, 3, 26-30.
[4]. M. Rafieian-Kopaei, J. Herbal Med. Pharmacol., 2012, 1, 1–2.
[5]. T.A. Tor-Anyiin, J.O. Igoli, J.N. Anyam, J. Chem. Soc. Nigeria.2015, 40, 71-75
[6]. T.Y. Dikko, E.M. Khan, A.T. Tor.Anyiin, V.J. Anyam, A.U. Linus, British J. Pharm. Res., 2016, 14, 1-10. 
[7]. J.A. Akande, Y. Hayashi, World J. Microbiol. Biotechnol., 1998, 14, 235-238.
[8]. A.D. Ali, E.B. Elisha, I. Abiem, S. Habila, O.M. Okeke, Res. Plant Sci., 2016, 4, 10-16.
[9]. M. Arbonnier, Trees, shrubs and lianas of West African dry zones. Margraf Publishers; 2004, 3, 8236-1419. 3. Jones EW.
[10]. Cece Forest Reserve, Northern Nigeria, Rafieian-J. Ecol., 1993, 51, 461-466.
[11]. D. Krishnaiah, T. Devi, A. Bono, R. Sarbatly J. Med. Plants Res., 2009, 3, 067-072.
[12]. O.S. Awotunde, S.O. Adewoye, J. Hawumba, J. Med. Plants Stud., 2016, 4, 243-247.
[13]. K. Batawila, K. Kokou, K. Koumaglo, M. Gbeassor, B. De Foucault, P. Bouchet, K. Akpagana, Fitoterapia2005, 76, 264-268.
[14]. A.W. Ojewumi, M. Kadiri, Int. J. Green Herbal Chem., 2014, 3, 1679-1689
[15]. I.S. Abdel-Hassan, J.A. Abdel-Barry, S.T. Mohammeda, J. Ethnopharm., 2000, 71, 325.
[16]. H.M. Adamu, O.A. Ushie, D.S. Lawal, I.A. Oga, Int. J. Tradit. Natur. Med., 2013, 3, 19-25.
[17]. D.S. Satyajit, L. Zahid, I. G. Alexander Natural Product Isolation 2nd Edition. 2006, pp 30-33.
[18]. J.N. Anyam, T.A. Tor-anyiin, J.O. Igoli, Int. J. Curr. Res. Chem. Pharm. Sci., 2015, 2, 32-37.
[19]. M.E. Khan, U.D. Yakubu, D. Kubmarawa, Bristish J. Appl. Sci. Technol, 2015, 5, 396-402.
 [20]. S. Kumar, R. Malhotra, D. Kumar (2010) Pharmacogn. Rev., 2010, 4, 58-61.
[21]. Z. Aliyu, M. Yushau, S. Aliyu, Open Conference Proceed. J., 2013, 4, 72-73
[22]. U.A. Linus, Y.J. Dikko, M.E. Khan, V.A. John, J.O.  Igoli, British Biotechnol. J., 2016,16, 1-8.
[23]. L.P. Luhata, N.M. Munkombwe, J. Innovat. Pharmaceut. Biolog. Sci., 2015, 2, 88-95.
[24]. C. Cayme, Jan-Michael, Y.R. Consolacion. Structure elucidation of β-stigmasterol and β -sitosterol from Scsbania urandittorallinn. [Pers.] and β-carotene from Hcliotronium indicumlinn by NMR spectroscopy. Kimika: 20 (1/2),            2004, pp. 5-12
[25]. E.H.E. Isam. Y.I. Christina, Pakistan J. Analyt. Environ. Chem., 2016, 17, 43–49.